What Causes Seasonal Allergies?

Understanding seasonal triggers

Hay fever. Seasonal allergies. Allergic rhinitis. Whatever you choose to call it, the symptoms of this common immunological disorder affect about 40 million people in the United States alone.1 But what causes the body's immune system to attack otherwise harmless substances such as pollen and mold, resulting in congestion (stuffy nose), rhinorrhea (runny nose), itchy nose, sneezing, and a host of other bothersome seasonal allergy symptoms? And what are some of the common allergens that can cause your seasonal allergy symptoms? These are the topics we'll be covering below.

Why me?

Genetics and environment both play a role in determining whether a person will develop seasonal allergies, with family history being the number-one predisposing factor.1 This genetic tendency, called atopy, refers to the body's capacity to produce immunoglobulin E (IgE) antibodies2. During a process called sensitization, these antibodies mistakenly identify certain allergens as invaders — and as a result, the immune system launches an allergy attack the next time the patient is exposed to those allergens.3

Common causes of seasonal allergies

Both outdoor and indoor allergens can trigger the symptoms of allergic rhinitis. Common allergy causes include4:

  • Trees (ash, birch, elm, hickory, maple, oak, poplar, sycamore, and walnut)
  • Grasses (Bermuda, orchard, red top, sweet vernal, and timothy)
  • Weeds (pigweed, ragweed, Russian thistle, sagebrush, and tumbleweed)
  • Molds (alternaria, aspergillus, and cladosporium)
  • Dust mites

When outdoor allergens are responsible, the condition may be referred to as hay fever or seasonal allergies. Only your doctor can diagnose seasonal allergies or pinpoint your triggers. But if you identify with any or all of the common seasonal allergy patterns below, it could be an indication that further evaluation is in order.

  • If you suffer more in the springtime, tree pollen may be your trouble.
  • If you sniffle more during the summer months, you may be allergic to grass and weed pollens.
  • If your symptoms flare up in late summer and fall, weed pollen or mold spores5 could be the culprit.
  • If you exhibit symptoms all year long, you may be allergic to indoor irritants such as dust mites and molds.6

Despite their designation as "seasonal" allergies, it's worth noting that pollens and conditions vary widely with locale. In fact, pollination may occur year round in parts of the southern United States, making seasonal allergies a year-round concern.7

1American Academy of Allergy, Asthma and Immunology. The Allergy Report Volume 1: Overview of Allergic Diseases: Diagnosis, Management, and Barriers to Care. Available at http://www.aaaai.org/ar/working_vol1/009.asp. Accessed February 15, 2008.

2Definition of Atopy; Definition of IgE. Available at http://www.medterms.com/script/main/art.asp?articlekey=31081 and http://www.medterms.com/script/main/art.asp?articlekey=21070. Accessed March 21, 2008.

3Hay Fever. MayoClinic.com. Available at http://www.mayoclinic.com/health/hayfever/DS00174/DSECTION=1. Accessed March 17, 2009.

4Airborne Allergens. PATADAY Web site. Available at http://www.pataday.com/airborne-allergens/Airborne-Allergies.asp. Accessed March 24, 2008.

5American Academy of Allergy, Asthma and Immunology. The Allergy Report Volume 1: Overview of Allergic Diseases: Diagnosis, Management, and Barriers to Care. Available at http://www.aaaai.org/ar/working_vol1/009.asp. Accessed February 15, 2008.

6American Academy of Allergy, Asthma and Immunology. Allergic Rhinitis Patient Fact Sheet. Available at http://www.aaaai.org/patients/resources/easy_reader/rhinitis.pdf. Accessed March 21, 2008.

7American Academy of Allergy, Asthma and Immunology. The Allergy Report Volume 1: Overview of Allergic Diseases: Diagnosis, Management, and Barriers to Care. Available at http://www.aaaai.org/ar/working_vol1/009.asp. Accessed February 15, 2008.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

PATIENT INFORMATION

PATANASE® (PAT-uh-nase) (olopatadine hydrochloride) Nasal Spray

For Use in the nose (Intranasal) only.

Read the Patient Information that comes with PATANASE® Nasal Spray carefully before you start using it and each time you get a refill. There may be new information. This leaflet does not take the place of talking to your health care provider about your medical condition or your treatment.

What is PATANASE® Nasal Spray?

PATANASE® Nasal Spray is a prescription medicine used to provide relief of seasonal allergy symptoms in adults and children 6 years of age and older.

PATANASE® Nasal Spray contains an antihistamine medicine that may help reduce nasal symptoms of seasonal allergic rhinitis.

What should I tell my health care provider before taking PATANASE® Nasal Spray?

Tell your health care provider about all your medical conditions, including if you are:

Tell your health care provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. PATANASE® Nasal Spray and other medicines may affect each other, causing side effects.

Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.

How should I use PATANASE® Nasal Spray?

Follow the Patient Instructions for Use below.

What are the possible side effects of

PATANASE® Nasal Spray?

Side effects of PATANASE® Nasal Spray include:

Tell your health care provider if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of PATANASE® Nasal Spray. For more information, ask your health care provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I avoid while using PATANASE® Nasal Spray?

PATANASE® Nasal Spray can make you sleepy.

Avoid the following while using PATANASE® Nasal Spray:

General information about PATANASE® Nasal Spray

Medicines are sometimes prescribed for conditions that are not mentioned in the patient leaflet. Do not use PATANASE® Nasal Spray for a condition for which it was not prescribed. Do not give PATANASE® Nasal Spray to other people, even if they have the same symptoms you have. It may harm them.

This patient information leaflet summarizes the most important information about PATANASE® Nasal Spray. If you would like more information about PATANASE® Nasal Spray talk with your health care provider. You can ask your health care provider or pharmacist for information about PATANASE® Nasal Spray that is written for health professionals. For more information go to www.PATANASE®.com or call 1-800-757-9195.

What are the ingredients of PATANASE® Nasal Spray?

Active ingredient: olopatadine hydrochloride 665 micrograms per 100 microliter spray.

Inactive ingredients: 0.01% benzalkonium chloride, sodium phosphate, dibasic, edetate disodium, sodium chloride, hydrochloric acid, sodium hydroxide and water.

What should I know about seasonal allergic rhinitis?

"Rhinitis" means inflammation of the lining of the nose. Seasonal allergic rhinitis is sometimes called "hay fever". Seasonal allergic rhinitis can be caused by allergies to pollen. If you have allergic rhinitis, your nose becomes stuffy, runny and itchy. You may also sneeze a lot. You may also have red, itchy, watery eyes and itchy throat, or blocked itchy ears.

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Alcon Laboratories, Inc.
Fort Worth, TX 76134 USA

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© 2008, Alcon, Inc.